Webinar Details
In this free live webinar, we will cover:
Human-Relevant Maturity: Learn how 3D bioengineered tissues reach a stable, adult-like metabolic and structural state by day 21.
Predictive Metabolic Function: Explore breakthroughs in capturing robust insulin-stimulated glucose uptake and mature GLUT4 localization for diabetes research.
Exercise Physiology In Vitro: See how exercise-mimicking stimulation and detraining mirror real-world human muscle plasticity and reversibility.
New Biological Insights: Discover the role of GYS1 and glycogen metabolism in sustaining muscle endurance under metabolic stress.
Join this webinar for the opportunity to learn more and join the live Q&A.
Summary
The translational gap between animal models and human clinical outcomes often stems from fundamental interspecies differences in fiber composition and metabolic regulation. This webinar features a landmark study from Novo Nordisk and the University of Copenhagen, utilizing Curi Bio’s Mantarray 3D skeletal muscle ecosystem.
We will detail a comprehensive workflow for generating functionally mature human muscle tissues that stabilize for longitudinal study. By integrating physiological, pharmacological, and genetic perturbations, the research team demonstrated that these tissues not only mirror human-like responses to insulin and exercise but also reveal new mechanisms of metabolic resilience. This session will provide a roadmap for using New Approach Methodologies (NAMs) to advance drug discovery for obesity, diabetes, and neuromuscular diseases.
Date & Time
Wednesday, June 24, 2026 at 8:00-9:00am PT (11:00am ET / 5:00pm CET)
Speaker Details
Dr. Thomas Leahy
Field Applications Scientist at Curi Bio
Dr. Thomas Leahy
Field Applications Scientist at Curi Bio
Dr. Leahy is a Field Applications Scientist at Curi Bio with a background in musculoskeletal and cardiovascular research, biomechanics, and 3D tissue engineering. He supports the adoption of Curi Bio’s technologies by collaborating with internal scientists and partnering directly with customers to expand applications across cardiac, skeletal muscle, and neuromuscular research.
Dr. Christos Michas
Product Manager at Curi Bio
Dr. Christos Michas
Product Manager at Curi Bio
Dr. Michas is the Product Manager for Curi Bio’s Curiverse™ hardware platforms — Nautilai™, Stingray™, Mantarray™, and the new Nautilai Plus™ ecosystem. He has led the development and launch of the 96-well functional biology platform, working across biology, engineering, and customer-facing teams to bring multimodal contractility and optical readouts to scale.