Webinar Details
In this free live webinar, we will cover:
Human-Relevant Maturity: Learn how 3D bioengineered tissues reach a stable, adult-like metabolic and structural state by day 21.
Predictive Metabolic Function: Explore breakthroughs in capturing robust insulin-stimulated glucose uptake and mature GLUT4 localization for diabetes research.
Exercise Physiology In Vitro: See how exercise-mimicking stimulation and detraining mirror real-world human muscle plasticity and reversibility.
New Biological Insights: Discover the role of GYS1 and glycogen metabolism in sustaining muscle endurance under metabolic stress.
Join this webinar for the opportunity to learn more and join the live Q&A.
Summary
The translational gap between animal models and human clinical outcomes often stems from fundamental interspecies differences in fiber composition and metabolic regulation. This webinar features a landmark study from Novo Nordisk and the University of Copenhagen, utilizing Curi Bio’s Mantarray 3D skeletal muscle ecosystem.
We will detail a comprehensive workflow for generating functionally mature human muscle tissues that stabilize for longitudinal study. By integrating physiological, pharmacological, and genetic perturbations, the research team demonstrated that these tissues not only mirror human-like responses to insulin and exercise but also reveal new mechanisms of metabolic resilience. This session will provide a roadmap for using New Approach Methodologies (NAMs) to advance drug discovery for obesity, diabetes, and neuromuscular diseases.
Date & Time
Wednesday, March 18, 2026 at 8:00-9:00am PT (11:00am ET / 5:00pm CET)
Speaker Details
Dr. Thomas Leahy
Field Applications Scientist at Curi Bio
Dr. Thomas Leahy
Field Applications Scientist at Curi Bio
Dr. Leahy is a Field Applications Scientist at Curi Bio with a background in musculoskeletal and cardiovascular research, biomechanics, and 3D tissue engineering. He supports the adoption of Curi Bio’s technologies by collaborating with internal scientists and partnering directly with customers to expand applications across cardiac, skeletal muscle, and neuromuscular research.
Dr. Jonas Borup Roland
Senior Scientist at Novo Nordisk
Dr. Jonas Borup Roland
Senior Scientist at Novo Nordisk
Jonas Roland is currently a research scientist within the Diabetes and Obesity therapeutic area in Novo Nordisk. His background is within muscle biology and he has extensive expertise in building relevant muscle models for research and drug development purposes.
Dr. Carlos Henríquez-Olguín
Dr. Carlos Henríquez-Olguín
Carlos Henríquez-Olguín has a PhD in Molecular Physiology and is a muscle biologist with a strong interest in metabolic research, drug discovery, and new therapeutic modalities.
Register Now to Secure Your Spot
Submit the form below to register for this live webinar + Q&A session. Registration will close 24 hours before the event.
Please contact us with any questions or concerns.