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Platforms Overview Biosystem Platforms Mantarray™ – 3D Tissue Contractility Analysis Mantarray Mini Plates – Fewer Cells. More Data. Nautilai Plus™ – 3D Tissue Contractility and Fluorescence at Scale Nautilai™ – Voltage & Calcium Imaging Stingray™ – Stimulation and Maturation of 3D Engineered Tissues NanoSurface™ Plates – HCI Plates for Structural Maturation Data Analytics Platforms Pulse™ – High-throughput Waveform and Video Analysis
Models Overview Applications Neuromuscular Junction Model DM1 Model Skeletal Muscle Models Cardiac Models Disease Models Cells & Media Metabolic Media 3D Skeletal Muscle Tissue Media Skeletal Muscle Myoblasts 3D Cardiac Media MYBPC3 HCM Cardiomyocytes Celogics Celo.Cardiomyocytes
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PLATFORMS Platforms Overview Biosystem Platforms Mantarray™ – 3D Tissue Contractility Analysis Mantarray Mini Plates – Fewer Cells. More Data. Nautilai Plus™ – 3D Tissue Contractility and Fluorescence at Scale Nautilai™ – Voltage & Calcium Imaging Stingray™ – Stimulation and Maturation of 3D Engineered Tissues NanoSurface™ Plates – HCI Plates for Structural Maturation Data Analytics Platforms Pulse™ – High-throughput Waveform and Video Analysis MODELS Models Overview Applications Neuromuscular Junction Model DM1 Model Skeletal Muscle Models Cardiac Models Disease Models Cells & Media Metabolic Media 3D Skeletal Muscle Tissue Media Skeletal Muscle Myoblasts 3D Cardiac Media MYBPC3 HCM Cardiomyocytes Celogics Celo.Cardiomyocytes SERVICES Curi Engine Services Curi Engine™ Services RESOURCES Publications Publications Application Notes Product Literature Webinars Posters Videos Knowledge Base ABOUT Company Company Events – Workshop World Tour News Blog Distributors Careers
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Peer-Reviewed Publications

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Matrix Nanotopography as a Regulator of Cell Function

Deok-Ho Kim et al. JCB, 197(3), 351-360 Publication Date: 2012 (Link To Paper)

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NanoSurface PlatesArianna KieserApril 30, 2012NIH 3T3, CHO, hMSC
Quantitative Analysis of the Combined Effect of Substrate Rigidity and Topographic Guidance on Cell Morphology

JinSeok Park et al. IEEE Transactions on NanoBioscience Volume: 11 , Issue: 1 , March 2012 (Link To Paper)

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NanoSurface PlatesArianna KieserSeptember 8, 2011CHO
Synergistically Enhanced Osteogenic Differentiation of Human Mesenchymal Stem Cells by Culture on Nanostructured Surfaces with Induction Media

Mi-Hyeon Yu et al. Biomacromolecules, 12;11(7):1856-62 (2010) (Link To Paper)

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NanoSurface PlatesArianna KieserJune 22, 2010hMSC
Nanoscale Cues Regulate the Structure and Function of Macroscopic Cardiac Tissue Constructs

Deok-Ho Kim et al. Proc Natl Acad Sci U S A, 107(2):565-70(2010) (Link To Paper)

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NanoSurface PlatesArianna KieserJanuary 12, 2010NRVMs
Mechanosensitivity of Fibroblast Cell Shape and Movement to Anisotropic Substratum Topography Gradients

Deok-Ho Kim et al. Biomaterials, 30(29):5433-44(2009) (Link To Paper)

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NanoSurface PlatesArianna KieserOctober 31, 2009NIH 3T3
Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy

Deok-Ho Kim et al. Adv Funct Mater., 19(10): 1579–1586(2009) (Link To Paper)

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NanoSurface PlatesArianna KieserFebruary 6, 2009NIH 3T3
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Mantarray™
3D Engineered Tissue Contractility Analysis

Cytostretcher™
Cell Stretching Instruments

NanoSurface™ Plates
Structural Maturation of Cardiac & Skeletal Muscle Cultures

We can help.
Utilize the Curi Engine™ for:

  • Compound Profiling/Screening
  • Assay/Model Development
  • Discovery

Cardiac Tissue Models

  • 2D Heart Models
  • 3D Engineered Heart Tissues (EHTs)

Skeletal Muscle Tissue Models

  • 2D Skeletal Muscle Models
  • 3D Engineered Muscle Tissues (EMTs)

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