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The Curi Engine: Ready-to-Screen Assays

Jumpstart Your Screening with Human Functional Data

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Validated Disease Models

Why build from scratch when the model is already on the shelf? We have a growing library of "ready-to-screen" 3D tissue models for a range of cardiac and skeletal muscle disorders.

Duchenne Muscular Dystrophy (DMD)

Our workhorse model. These tissues show clear functional deficits in force, fatigue, and recovery, ideal for testing gene therapies, ASOs, or small molecules.

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Myotonic Dystrophy Type 1 (DM1)

A robust model demonstrating the key functional phenotypes of the disease.

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X-Linked Myotubular Myopathy (XL-MTM)

A severe myopathy model for testing novel therapeutic interventions.

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Hypertrophic Cardiomyopathy (HCM)

Featuring mutations like MYBPC3, these 3D heart tissues show the classic HCM phenotype: hyper-contractility and impaired relaxation.

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Muscle Metabolism & Fatigue

Using our specialized Curi Bio Metabolic Media, we probe mitochondrial function, glucose uptake, and metabolic exhaustion.

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And Many More...

We're constantly developing models for ALS, Pompe disease, complex co-culture models (e.g., FAP-muscle interaction), and more.

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Ready to Advance Your Program With Human Data?

Contact us to Schedule a Consultation

Let's discuss your project.

Curi Bio is ready to partner with you to design a study that answers your most critical questions.